Global Monoclonal Antibodies (mAbs) Market, 2020-2034, (USD Million)

Global Monoclonal Antibodies (mAbs) Market Soars Toward Multi-Billion-Dollar Heights by 2034

By Type (Fully Humanized mAbs, Chimeric Humanized mAbs),By Application (Oncology, Autoimmune Diseases, Cardiovascular Diseases, Infectious Diseases, Neurological Disorders, Others, Total),By Region (North America, Europe, Asia Pacific, Latin America, Middle East & Africa), And Segment Forecasts, 2020 – 2034.

Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa. The North American monoclonal antibodies (mAbs) market was valued at USD 17,265.56 million in 2020 and is expected to reach USD 73,611.39 million by 2034. It will grow at an 11.51% CAGR (2025–2034) and hold a 41.59% share in 2023.  Europe’s monoclonal antibodies (mAbs) market was USD 11,600.00 million in 2020 and is projected to climb to USD 47,633.99 million by 2034. With an 11.22% CAGR (2025–2034), it accounted for about 27.72% of the market in 2023. Asia Pacific monoclonal antibodies (mAbs) market in Asia Pacific was USD 8,892.85 million in 2020 and is anticipated to reach USD 39,367.09 million by 2034. It is projected to grow at an 11.81% CAGR (2025–2034), this region holds roughly 21.58% share in 2023. 

Regional Share (%)

“Funnel chart showing the regional share (%) of the global monoclonal antibodies (mAbs) market, with North America at the widest segment (100%), followed by Europe (66.7%), Asia Pacific (51.9%), Latin America (9.3%), and the Middle East & Africa (12.6%).”

“Global mAbs market funnel chart, highlighting North America’s leading share, followed by Europe, Asia Pacific, Latin America, and the Middle East & Africa.”

 Source: Primary Research and Secondary Research and GDRA 

Latin America monoclonal antibodies (mAbs) market in Latin America totaled USD 1,657.40 million in 2020 and is set to hit USD 6,120.76 million by 2034. It is poised for a 10.38% CAGR (2025–2034) and will represent about 3.87% of the market in 2023. In addition, the Middle East and Africa monoclonal antibodies (mAbs) market was USD 2,221.18 million in 2020 and is on track to reach USD 8,605.83 million by 2034. Growing at a 10.76% CAGR (2025–2034), this region will capture a 5.24% share in 2023.

Oncology & Fully Humanized mAbs Drive Segment-Wise Expansion

The market is segmented by type into Fully Humanized monoclonal antibodies (mAbs) and Chimeraized Humanized mAbs (mAbs). The fully humanized monoclonal antibodies (mAbs) market was USD 24,193.14 million in 2020 and is anticipated to reach USD 103,961.37 million by 2034. It will expand at an 11.58% CAGR (2025–2034), commanding a 58.36% share in 2023.

Type Segment Share (%), 2023

“Pie chart comparing the 2023 market share of fully humanized mAbs (58.4%) and chimeric humanized mAbs (41.6%).”
“Market share of fully humanized vs. chimeric humanized monoclonal antibodies (mAbs) in 2023.”

Source: Primary Research and Secondary Research and GDRA 

On the other hand, the Chimeric Humanized mAbs monoclonal antibodies (mAbs) market for chimeric humanized variants was USD 17,449.84 million in 2020 and is likely to top USD 71,317.89 million by 2034. Projected to grow at an 11.18% CAGR (2025–2034), this segment held a nearly 41.64% share in 2023.

Oncology & Fully Humanized mAbs Drive Segment-Wise Expansion

The market is segmented by application into Oncology, Autoimmune Diseases, Cardiovascular Diseases, Infectious Diseases, Neurological Disorders, and Others. The oncology monoclonal antibodies (mAbs) market in oncology reached USD 15,740.42 Million in 2020, set to hit USD 70,056.57 Million by 2034. With an 11.84% CAGR (2025–2034), it dominates the application segment and will account for around 38.30% of the market in 2023.

 Application Market Size (USD Million)

“A grouped bar chart illustrating the market size (in USD million) of monoclonal antibodies from 2020 to 2023, broken down by application: Oncology, Autoimmune Diseases, Cardiovascular Diseases, Infectious Diseases, Neurological Disorders, and Others.”
“Yearly comparison of the mAbs market size (in USD million) by major therapeutic applications from 2020 through 2023.”

Source: Primary Research and Secondary Research and GDRA 

  • Autoimmune Diseases monoclonal antibodies (mAbs) market for autoimmune diseases tallied USD 11,794.40 Million in 2020, predicted to reach USD 51,194.83 Million by 2034. Growing at an 11.66% CAGR (2025–2034), the segment will represent about 28.51% of the market in 2023.
  • The monoclonal antibodies (mAbs) market for cardiovascular diseases, valued at USD 5,236.10 million in 2020, may surge to USD 20,234.92 million by 2034. It is forecast to grow at an 11.36% CAGR (2025–2034), capturing some 12.36% share in 2023.
  • The Infectious Diseases monoclonal antibodies (mAbs) market was USD 3,865.64 million in 2020 and is estimated to touch USD 15,843.34 million by 2034. It is anticipated to grow at an 11.20% CAGR (2025–2034) and hold an approximately 9.23% share in 2023.
  • The monoclonal antibodies (mAbs) market for neurological disorders was USD 3,083.36 million in 2020 and is slated to reach USD 11,242.86 million by 2034. Registering a 10.28% CAGR (2025–2034), this segment accounts for around 7.18% of the market in 2023.
  • In addition, the other monoclonal antibodies (mAbs) market in other applications was USD 1,923.02 million in 2020 and is poised to climb to USD 6,597.44 million by 2034. Growing at a 9.80% CAGR (2025–2034), it represented nearly a 4.42% share in 2023.

Global Monoclonal Antibodies (mAbs) Market Segmentation

  1. By Type
    • Fully Humanized mAbs
    • Chimeric Humanized mAbs
    • Others (e.g., Murine, Fully Human, Bispecific mAbs)
  2. By Application
    • Oncology
    • Autoimmune Diseases
    • Cardiovascular Diseases
    • Infectious Diseases
    • Neurological Disorders
    • Others

Key Players in the Monoclonal Antibodies (mAbs) Market

  1. AbbVie Inc.
  2. Amgen Inc.
  3. Hoffmann-La Roche Ltd (Genentech)
  4. Bristol Myers Squibb (BMS)
  5. Johnson & Johnson (Janssen)
  6. Merck & Co., Inc.
  7. Pfizer Inc.
  8. Sanofi
  9. Novartis AG
  10. Eli Lilly and Company
  11. AstraZeneca plc
  12. GSK plc (GlaxoSmithKline)
  13. Biogen Inc.
  14. UCB S.A.
  15. Teva Pharmaceutical Industries Ltd.

These companies drive market growth through extensive R&D, strategic collaborations, and a focus on developing targeted therapies for a wide array of therapeutic indications.

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